Which organism produces cholera toxin, an exotoxin?

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Prepare for the WGU NURS1010 Microbiology Exam with engaging study materials, flashcards, and multiple choice questions. Enhance your understanding with detailed explanations and insights. Get exam-ready today!

Multiple Choice

Which organism produces cholera toxin, an exotoxin?

Explanation:
Cholera toxin is a secreted exotoxin produced by Vibrio cholerae. It is an AB5 toxin that ADP-ribosylates the Gs alpha subunit, causing constitutive activation of adenylate cyclase and a rise in cAMP within intestinal epithelial cells. The increased cAMP opens chloride channels, leading to massive water and electrolyte loss into the gut and the characteristic profuse watery diarrhea. Other organisms listed produce different toxins or do not produce cholera toxin, so Vibrio cholerae is the correct source.

Cholera toxin is a secreted exotoxin produced by Vibrio cholerae. It is an AB5 toxin that ADP-ribosylates the Gs alpha subunit, causing constitutive activation of adenylate cyclase and a rise in cAMP within intestinal epithelial cells. The increased cAMP opens chloride channels, leading to massive water and electrolyte loss into the gut and the characteristic profuse watery diarrhea. Other organisms listed produce different toxins or do not produce cholera toxin, so Vibrio cholerae is the correct source.

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