What is the primary consequence of "leaky" capillaries during inflammation?

• A. Reduced blood flow
• B. Increased gas exchange
• C. Fluid accumulation in tissues
• D. Increased immune cell movement

Answer: (C)

The primary consequence of "leaky" capillaries during inflammation is fluid accumulation in tissues. During the inflammatory response, various chemical mediators are released, which increase the permeability of the capillaries. This allows fluids, proteins, and white blood cells to exit the bloodstream and enter the surrounding tissues. As a result, the affected area becomes swollen and edematous due to the increased fluid that accumulates. This fluid accumulation is essential for delivering immune cells and nutrients to the injured site, aiding in healing and the inflammatory process.

While increased immune cell movement does occur as a result of the leaky capillaries, it is secondary to the initial fluid accumulation. Therefore, the correct focus on fluid accumulation provides a clearer picture of the immediate consequences of capillary permeability changes during inflammation.